Assuming your default web port on Apache is 80, enter the following definition in the file named httpd-vhosts.conf (in <Apache Installation>/config below any other virtual hosts:
<VirtualHost *:80>
ServerName yourapp
DocumentRoot "E:\phpdev\yourapplication"
</VirtualHost>
<Directory "E:\phpdev\yourapplication">
Options Indexes FollowSymLinks
AllowOverride All
Order allow,deny
Allow from all
</Directory>